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Icariin
Icariin Basic information
Description References
Product Name: Icariin
Synonyms: Horny goat weed extract;ICARIINE;ICARRIN;epimedium extract;Epimedium herb Ext;Epimedium P.E;Icariin, froM EpiMediuM davidii Franch;Icariin Min 90%
CAS: 489-32-7
MF: C33H40O15
MW: 676.66
EINECS:
Product Categories: phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Standardized plant extract;Inhibitors;API;Flavones;Functional Products;Natural Plant Extract;The group of Epimedii;plant extract;Nutritional Ingredients;Plant extracts;chemical reagent;pharmaceutical intermediate
Mol File: 489-32-7.mol
Icariin Chemical Properties
Melting point 223-225 ºC
alpha D15 -87.09° (in pyridine)
density 1.55
RTECS DJ2980500
storage temp. room temp
solubility DMSO: soluble50mg/mL, clear, colorless to dark yellow
form Powder
color light yellow to yellow
Icariin Usage And Synthesis
Description Icariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. Icariin is reported to prevent and treat sexual dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases.
References [1] K. M. Chen, B. F. Ge, H. P. Ma, X. Y. Liu, M. H. Bai, Y, Wang (2005) Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells, 60, 939-942
[2] Patent CN 1199647C “Application of icariin in preparation of medicine for preventing and treating sexual dysfunction”
[3] Patent CN 104739851 A “New application of icariin, or icariin derivatives or icariin salt”
Chemical Properties Light yellow to yellow solid
Uses hepatoprotective
